About 2,500 people were injured when the strong 7.8-magnitude quake hit Saturday evening, Vice President Jorge Glas said, a sharp rise over the previous official figure of 1,557 hurt when buildings came crashing down.
Although the oil-producing South American nation frequently suffers seismic shudders because of its position on the so-called Ring of Fire that skirts much of the Pacific basin, the quake -- though it lasted just one minute -- was the worst in nearly 40 years in Ecuador.
The quake wrecked buildings, toppled power lines and sent terrified residents running from their homes when it struck a coastal zone popular with tourists.
Some 100 inmates in a prison in the western town of Portoviejo escaped when the quake shook their facility, Justice Minister Ledy Zuniga tweeted.
About 30 of them had been recaptured, some had returned voluntarily and police were hunting the others.
Elsewhere in hard-hit Portoviejo, rescuers raced to find survivors.
"We have already recovered three dead and we believe there are 10 to 11 people still trapped," said one worker digging through the debris of what used to be a six-story hotel.
The smell of decaying bodies started to lace the tropical air.
Officials declared a state of emergency in the worst-hit provinces, and a national state of "exception," both of which suspend certain civil rights and liberties to allow security forces and officials to react faster.
Among the worst-hit towns was Pedernales, where Mayor Gabriel Alcivar estimated there were up to 400 more dead yet to be confirmed, many under the rubble of hotels that collapsed.
"Pedernales is devastated. Buildings have fallen down, especially hotels where there are lots of tourists staying. There are lots of dead bodies," he told local media.
"We need help. We need medicine, water and food to help people."
Ecuador's Geophysical Office reported "considerable" structural damage as far away as Guayaquil, Ecuador's biggest city with more than two million people, which is 350 kilometres away.
Two Canadians were among those killed by the quake, their country's government said.
In the town of Abdon Calderon, near Portoviejo, 73-year-old resident Nelly, who would not give her last name, said in tears that she rushed into the street after the quake and saw that the covered market had collapsed.
Neighbouring Colombia -- which also felt the quake but emerged unscathed -- and Mexico have dispatched aid and emergency workers to help in the rescue effort.
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