ERA test best for women unable to conceive through IVF

Endometrial Receptivity Analysis (ERA) is the best solution for women unable to conceive even after In Vitro Fertilisation (IVF) treatment due to wrong window implantation, reveals a study by Igenomix.

According to the reproductive genetic laboratory giant Igenomix, the only reason why women cannot get pregnant despite repeated IVF attempts is the wrong window implantation.

Medical science says that an IVF implantation is successful only when the endometrium is receptive.

Endometrium is the inner lining which prepares every month to accept the embryo, moreover, this is the place where the embryo implants and resides during gestation.

A successful embryo implantation depends on several factors and the most important factor is the correct window of implantation. Many a times women opting for assisted methods of achieving pregnancy are disappointed because the treatments do not yield positive results.

Endometrial Receptivity Analysis (ERA) determines whether a woman is receptive on the day when the biopsy is performed. If the result is positive then it is the window of implantation for that particular patient.

Therefore ERA is a very personalised genetic test that leads to a "personalised embryo transfer" (PET), a timing based on the test performed on an individual. If the result of the test is non-receptive then a second biopsy is suggested to validate the displacement.

Embryo implantation can only be successful if it is carried out between 19-21 days of the menstrual cycle. This is the window of implantation.

Igenomix has so far handled over 12,000 cases of ERA worldwide. Out of these at least 2,500 of them were from India alone.

"In general we find approximately 26 per cent of patients as Non-Receptive and therefore suffering from repetitive implantation failure. In patients where result is receptive the rate of implantation is significantly higher, close to 45 per cent and chances of a successful pregnancy are 60 per cent" Dr. Rajni Khajuria, Igenomix said.

"With 10 years of research in this field, Igenomix has given hope to couples who have been trying to have a child through assisted means, by introducing a patented test named Endometrial Receptivity Analysis-ERA. ERA is a state of art diagnostic method evaluating the endometrial receptivity," said Khajuria.

--IANS

rup/ask/dg