Doctors Without Borders, known by its French acronym MSF, said it was evacuating medics and patients from the Al Salamah in northern Syria as the Islamic State militants neared.
It said a basic team would remain to help the ill and wounded and that around 100,000 people were under threat from the IS offensive.
"MSF has had to evacuate most patients and staff from our hospital as frontlines have come too close," Pablo Marco, MSF operations manager for the Middle East, said in a statement.
"We are terribly concerned about the fate of our hospital and our patients, and about the estimated 100,000 people trapped between the Turkish border and active frontlines. There is nowhere for people to flee to as the fighting gets closer," Marco added.
In a statement, IS claimed to have taken control of seven villages from the Free Syrian Army and "apostate" fighters.
In Kaljibrin, there were reports that militants had publicly executed rebel fighters and their families, including women and children, in a main square.
Militants said it had seized American-made weapons from "US-vetted" groups in the advance, although it was impossible to verify the claim.
The IS offensive has split rebel-held territory in northern Aleppo governorate into two, leaving a thin sliver linking the city of Azaz to the Turkish border and town of Marea, bordered on the other side by Kurdish groups.
Syrian rebel factions in the area, which includes the border crossing of Bab al-Salama, have also come under fire from pro-government forces and the predominantly Kurdish Syrian Democratic Forces in recent months.
A London-based Syrian Observatory for Human Rights said Friday's advance also effectively cut off a key supply route between Azaz and Marea, another opposition stronghold.
Both Azaz and the Bab al-Salama crossing have been a lifeline for the opposition since the town fell into rebel hands in 2012 but are being threatened by Russian air strikes and fighting.
MSF and other aid organisations warned earlier this month that the humanitarian situation for over 100,000 people trapped in the Azaz rebel-held pocket was critical.
Staffan de Mistura, the UN envoy for Syria, said he plans for a resumption of peace talks "as soon as feasible" between the Government and opposition but expects that it will "certainly not" come within the next two to three weeks.
IS and the Al Qaeda linked Jabhat al-Nusra are excluded from negotiations, which were suspended last month between Bashar al-Assad's government and other rebels
--IANS
ahm/vt
You’ve reached your limit of {{free_limit}} free articles this month.
Subscribe now for unlimited access.
Already subscribed? Log in
Subscribe to read the full story →
Smart Quarterly
₹900
3 Months
₹300/Month
Smart Essential
₹2,700
1 Year
₹225/Month
Super Saver
₹3,900
2 Years
₹162/Month
Renews automatically, cancel anytime
Here’s what’s included in our digital subscription plans
Exclusive premium stories online
Over 30 premium stories daily, handpicked by our editors


Complimentary Access to The New York Times
News, Games, Cooking, Audio, Wirecutter & The Athletic
Business Standard Epaper
Digital replica of our daily newspaper — with options to read, save, and share


Curated Newsletters
Insights on markets, finance, politics, tech, and more delivered to your inbox
Market Analysis & Investment Insights
In-depth market analysis & insights with access to The Smart Investor


Archives
Repository of articles and publications dating back to 1997
Ad-free Reading
Uninterrupted reading experience with no advertisements


Seamless Access Across All Devices
Access Business Standard across devices — mobile, tablet, or PC, via web or app
