In reality, multiple crises confront humanity today, such as climate change, environmental degradation, declining water, food and energy security and social and economic inequality. These are all densely inter-connected, sometimes mutually reinforcing, while at other times mutually off-setting. They are symptoms of a deeper civilisational malaise embedded in our way of life, our value system, our understanding of the past and our aspirations for the future. Dealing with each crisis as if it were a singular phenomenon occurring in a single domain will not work because it is linked through feedback loops to multiple domains. A crisis in one part of our planet’s ecology such as the outbreak of Covid-19, may be linked to phenomena occurring in other domains, although this may not be immediately obvious. There was an interdependent causal chain at work here. The Covid-19 was a virus hosted by a species normally resident in the wild, in this case wild bats. These bats were brought into close proximity with industrially raised animals packed together at a food market in Wuhan, China, heightening the risk of contagion. The risk is inherent in the nature of processes developed to enhance food security without regard to consequences in other domains.This inability to look at our challenges in a comprehensive frame is inherent in our current knowledge systems, which progress through ever-increasing specialisation and focus on the micro, abstracting from the macro. The big picture, the awareness of the myriad threads that bind the planet’s fragile ecology together, that a small disturbance in one part of this ecology may trigger large disruptions in other parts, this compelling truth has been increasingly obscured and is now being denied in a fit of collective blindness. The reason is not hard to find. Acknowledging the truth will demand that we alter our lifestyles, change our value systems and reconnect humanity with nature —Man in Nature, not Man Against Nature, which has been the credo of our industrial age.