The refugees have been offered new lives in the United States and other nations after the failure of years of negotiations to secure their return to Bhutan, which says they are illegal immigrants.
Less than 18,000 refugees remain in the camps, according to a joint statement from the UN Refugee Agency (UNHCR) and the International Organization for Migration.
All are ethnic Nepalese who fled across the border in the early 1990s, claiming persecution after Bhutan made national dress compulsory and banned the Nepalese language.
The programme began in 2007 following the failure of years of high-level negotiations to secure their return to Bhutan.
More than 84,000 refugees have left for the US, while Australia, Canada, Denmark, New Zealand, the Netherlands, Norway, Denmark and Britain have also taken thousands.
Refugee Devi Maya Thapa Thapa will head to the US with her family next month, becoming the 100,000th Bhutanese to be resettled.
