Authorities said about 50 buildings in the village of Hitrino were destroyed when containers of gas exploded at 5:40 AM.
Video footage showed many houses in the village of 800 on fire and ambulances taking the injured to hospitals. Hitrino Mayor Nuridin Ismail told reporters that children had been buried under the rubble of a house that collapsed.
Two tanker cars carrying propane-butane and propylene derailed at the station in Hitrino, hit nearby electric lines and exploded, police officials said. The engine driver survived and has been questioned, police said.
The entire village was evacuated later today as a precaution due to the risk of possible new explosions. Emergency teams started a high-risk operation to reload the hazardous substances.
Prime Minister Boiko Borisov, who arrived at the site of the blast, urged citizens to donate blood to address shortages at nearby hospitals.
"There will be more casualties," Borisov told reporters. He said several people suffered more than 90 percent burns and that damage from the explosion was extensive. The train had been traveling from the Bulgarian Black Sea port city of Burgas to the Danube city of Ruse.
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