The train accident happened "because of excessive speed" at Eckwersheim in eastern France as technicians were on board for testing, said a top local official Dominique-Nicolas Jane.
However, police said the cause of the crash had not been determined. A source close to the investigation said dozens of technicians were aboard.
The train ended up near a bridge in the water of a roughly 40-metre wide canal.
A police dive team, helicopters and tens of rescue vehicles were sent to the scene in response to the crash.
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