Cameron commended politicians in the House of Commons who were sporting growths on their upper lips of all colours and sizes.
He joked: "I have noticed a number of my colleagues suddenly resembling banditos and others on these benches.
"It's not something, I have to say, that I'm fully capable of myself. I'm jealous on those grounds as well. But this is important - better diagnoses, better knowledge, better information, are all vital to beat prostate cancer."
Responding to Freeman's question about prostate cancer, Cameron paid tribute to parliamentary colleagues who are "suddenly resembling banditos".
The Movember campaign encourages men to grow sponsored moustaches to raise money for causes related to male health problems, such as prostate and testicular cancer.
Last year, Madame Tussauds attached a fake moustache to Cameron's waxwork to promote Movember.
The London museum also adorned its waxwork of Boris Johnson, the London Mayor, with a bristling blond moustache for the occasion.
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