US presidential primaries: Hillary Clinton launches full scale attack against Donald Trump

Confident that she would finally bag the Democratic presidential nomination, Hillary Clinton appeared to have gone into a full campaign mode by training her gun on potential Republican opponent Donald Trump.

While she did not respond to Trump's latest "crooked" characterization of her, Clinton slammed the real estate billionaire for his views on Muslims, immigrants and women.

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"I'm not going to respond to what he said about me," the former secretary of state told her supporters at a restaurant in Pennsylvania, where both the Democratic and Republican primaries are scheduled for April 26.

The former New York Senator was apparently referring to the "crooked Clinton" remarks of Trump.

Both Clinton and Trump are leading against their primary opponents in Pennsylvania.

"I'm going to respond to what he has said about women in general. I'm going to respond to what he has said about immigrants. I'm going to respond to what he has said about Muslims. I'm going to respond on behalf of all the people who have been the target of his hatred and his demagoguery," Clinton said.

This was her first major attack against Trump after her win in New York this week.

But news reports said Trump is ready to fight out the former first lady.

"The only thing she's got going is the women card. We call her 'Crooked Hillary' because she's a crooked person. She's always been a crooked person," Trump told Fox News.

A day after the next round of primary elections in Maryland, Pennsylvania, Delaware, Connecticut and Rhode Island, Trump is scheduled to give a speech on foreign policy at the National Press Club on Wednesday, April 27.

"I am honored to be invited to speak at an organization founded by former President Richard Nixon, and look forward to sharing my views on the many serious foreign policy issues facing our country and our allies around the world," he said.

"Trade, immigration and security policies are critical concerns of all Americans, and we must develop a clear, consistent long-term foreign policy for making America safe and prosperous," he said in a statement.