The network has also decided not to renew Ioan Gruffudd's "Forever" for a second season, while "The Taste" has been axed, reported Variety.
Writing on Twitter, Gruffudd's wife Alice Evans admitted that he is "a little shaken" by the news, adding: "It's brutal, but that's show business."
The actor played Henry Morgan, an immortal New York City medical examiner in the series. Alana de la Garza, Joel David Moore, Donnie Keshawarz, Lorraine Toussaint and Judd Hirsch were also among the cast.
ABC's newest comedy "Cristela" is also coming to an end after just one season, and "Resurrection" will not be back for a third season. Culinary competition "The Taste" is being cancelled after two seasons.
Comedies "Black-ish", "Fresh Off the Boat", "The Goldberg", "The Middle", "Modern Family" and "Galavant" will also return, along with unscripted series "The Bachelor", "Dancing With the Stars", "America's Funniest Home Videos", "Shark Tank", "Beyond the Tank" and "20/20".
The only show ABC is yet to decide on is Tim Allen sitcom "Last Man Standing".
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