The 28-year-old woman, who arrived in Cuba on February 21, is hospitalized at the Pedro Kouri Tropical Medicine Institute in the capital Havana.
The doctor said her husband contracted Zika two months ago and that her brother-in-law also got sick two weeks before her trip to Cuba, the health ministry said in a statement carried by state newspaper Granma.
According to the statement, the woman was staying in a dorm in the western Cuban province of Artemisa together with 37 other doctors who are being monitored.
The rapidly expanding Zika virus -- which has affected more than 20 Latin American countries -- is suspected to be the cause of a sudden increase in cases of neonatal microcephaly, a severe deformation of the brain and skull among newborns.
Brazil has been the hardest hit.
Last week, Cuban President Raul Castro ordered the mobilization of some 9,000 soldiers to fight the Aedes aegypti mosquito that transmits the virus.
Countries throughout the region have launched operations to eliminate pools of stagnant water where the mosquitoes, which also spread dengue and chikungunya viruses, can breed.
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