During his opening monologue, host James Corden rapped about what to expect from the night and encouraged musicians to live it up, saying, "With President Trump, we don't know what comes next."
Corden, who's already called out Trump's travel ban, seemed to reference its divisiveness again, saying, "We sit here tonight, no matter our race or where we were born or colour or face. Music is art, remember forever. We can survive by sticking together."
She then quoted Toni Morrison: "This is precisely the time when artists go to work. There is no time for despair, no place for self-pity, no need for silence, no room for fear. We speak, we write, we do language. That is how civilizations heal."
"When things like this happen, it impacts us directly because a lot of us come from a lot of those countries," Indian tabla player Sandeep Das told reporters after his collaboration with Yo-Yo Ma's "Sing Me Home" won in the World Music category.
Beyonce concluded her highly anticipated performance with a reference to women's rights.
"1,000 girls raise their arms," she said. "If we're going to heal, let it be glorious."
Some stars got political at the Grammy Awards before the show even started.
On the red carpet, the musical group Highly Suspect made a political statement when band member Johnny Stevens wore a jacket that said "Impeach" across the back.
The back of the dress had "Trump" printed across it.
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