In a written statement, the Istanbul governor's office said 142 people were detained and 90 were wounded as confrontations escalated. Nineteen of the wounded were police officers.
The Dogan news agency, citing the Istanbul Medical Chamber, reported some serious injuries. The report said that more than a dozen people were wounded by tear gas canisters and hundreds had received treatment at clinics for exposure to gas. Turkish police have been widely criticised by international rights groups for heavy-handed tactics on protesters in previous demonstrations.
Last week city, administrators said the square would be off limits to International Workers' Day demonstrations and most points of entry were blocked.
Before being declared a national holiday in 2009, May 1 was a day of conflict that often led to violence across Turkey.
Taksim is symbolic for Turkey's labor movement. In 1977, 34 people were killed in the square during a May Day event when shots were fired into the crowd from a nearby building.
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