Alastair Cook's men suffered a 75-run defeat inside four days in last week's first Test at Lord's, with Pakistan leg-spinner Yasir Shah taking 10 wickets.
Now England will hope to play Shah better at Old Trafford, where the pitch is likely to offer more turn.
They also have to decide whether to give a home debut to leg-spinner Adil Rashid, either in support of, or as a replacement for, Moeen Ali.
England have now called in former Pakistan off-spinner Saqlain Mushtaq as a coaching consultant at Old Trafford.
While they will hope he can advise Ali and Rashid, his greatest short-term benefit may lie in tips about how to play spin.
England have been without a specialist spin coach since former Pakistan leg-spinner Mushtaq Ahmed, now in the tourists' camp, returned home in 2014.
Anderson is due to return on his Lancashire home ground amid suggestions that Cook and coach Trevor Bayliss were happy to accept his assurances that he was fit for Lord's, only for the pair to be over-ruled by the selectors.
Meanwhile Stokes was looking forward to working with Saqlain, who took four for 74 when Pakistan beat England by 108 runs in the second Test at Old Trafford in 2001.
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