The victims, Satyanarayan (50) and his son Satyam (22) died in the accident while the other son Abhishek (25) survived with severe injuries, police said.
According to a police spokesperson, the incident took place when the victims were on the way to their shop and a speeding city bus hit into a car and then rammed their motorcycle.
The victims were taken to the government hospital where doctors declared the father and the son brought dead while Abhishek was admitted in a serious condition, he said.
The bodies of the deceased have been sent for the post-mortem, they said, adding police is investigating the matter.