Gayle, who has a chronic back complaint, hit the highest-ever individual World Cup score of 215, containing a record-equalling 16 sixes, in Tuesday's thumping win over Zimbabwe in Canberra.
Holder said 35-year-old Gayle was being nursed through the tournament to ensure he was in the best possible shape to play.
"In terms of Chris's fitness, obviously he's been struggling over the past with his back. So we're trying to monitor him as best as we possibly can," Holder told reporters at the SCG.
"He doesn't train often. I played with him in Bangalore, and you don't often see him in the nets," he told reporters.
"His body is quite old for his age, I think. He needs to look after himself to make sure he gets on the path with all the games."
Gayle said he has had the back injury since January last year and was managing it.
"It's the same back injury. I've had it since last January. It can't seem to be solved, to be honest with you," he said this week.
Holder, 23, who was pitched into the hot seat as captain of the notoriously fractious Windies team, said Gayle exerted a big presence in the dressing room.
"We've always rallied around Chris. Chris is one of the most jovial people in the dressing room," Holder said
"He brings a different atmosphere. He brings a lot of fun. He's a big team man, and his presence is pretty much felt in the dressing room.
"I think it's important that his success is crucial to our overall success. We love him.
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