Givi Targamadze, who is running for office for the ex-Soviet republic's main opposition United National Movement (UNM) party, told journalists that an explosive device planted in the back of his car detonated last night.
Targamadze, who was sitting in the front of the vehicle, was unhurt.
Four passers-by were rushed to hospital, one with serious but not life-threatening injuries, Health Minister David Sergeyenko said in televised comments.
Prime Minister Giorgi Kvirikashvili today condemned the blast as "sabotage against the state" committed by the country's "enemies" who "will be held accountable to the fullest extent of the law".
UNM leader David Bakradze said that "no matter who was behind the car attack, the authorities are responsible for creating a climate of hatred in which opposition politicians are being attacked".
The bombing was not the first violent incident to occur in the lead-up to the vote.
On Sunday, unknown assailants fired shots during a campaign rally held by MP candidate Irakli Okruashvili in the central city of Gori, injuring two men.
Saturday's knife-edge parliamentary election will see the UNM and the ruling Georgian Dream party clash in a bitter power struggle.
Georgia's ex-president and UNM's founder Mikheil Saakashvili - who lives in exile in Ukraine - addressed via videolink tens of thousands of supporters who gathered in downtown Tbilisi for a campaign rally.
"Just a few days separate us from our (electoral) victory," he told crowds of people chanting his name.
"Georgia is approaching a historic moment, a moment of truth."
Saakashvili, who serves as a regional governor in Ukraine, is wanted by Georgian prosecutors for alleged abuse of office during his nine-year rule - charges he has denounced as trumped-up and politically motivated.
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