She was 76 and had been under treatment for two months for liver cancer, family sources said.
"Her death was sudden, she passed away this morning. She was getting treatment for liver cancer for the past two months," Ganesh and Krishnan of Y R Gaitonde Center for AIDS Research and Education (YRG Care) told PTI.
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She is survived by her son Dr Sunil Solomon. Her husband Dr Solomon Victor predeceased her in 2006.
Dr Suniti Solomon and her colleagues documented the first evidence of the HIV infection in India in 1986 when blood samples of six commercial sex workers staying in a government home here tested positive.
The samples were first sent to Christian Medical College in Vellore and later to a facility in the USA, where they tested HIV positive.
It quickly led to a series of research and training for medical and paramedical professionals on HIV infection, besides gradually putting in place a treatment regimen for those affected.
Her pioneering HIV research studies includes the US National Institute of Mental Health's multi-country HIV/STD Prevention Trial.
"When she served Madras Medical College and Government General Hospital as a Professor of Microbiology, she set up the first voluntary testing and counselling centre and an AIDS Research Group in Chennai," Ganesh said.
An MD in Microbiology from Madras University, she was a household name in Tamil Nadu in the area of HIV prevention and care and among people living with HIV/AIDS.
Trained in pathology in the UK and USA, her experience covers a wide range of aspects linked to HIV infection, biomedical parameters to socio-economics.
In the last three decades, there was hardly any event or academic programme on HIV in the state in which she had not participated.
She has published papers extensively on HIV epidemiology, prevention, care, support and related gender issues.
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