Hollande, who is visiting Cairo as part of a regional tour, attended a business forum with his Egyptian counterpart Abdel Fattah al-Sisi, with both countries hoping to boost trade and investments.
Allegations of human rights abuses under Sisi's government dominated a joint press conference on Sunday, with Hollande insisting that respecting rights was not a hindrance to fighting "terrorism".
But Egypt -- the most populous Arab country -- is seen as a cornerstone of regional security as well as a key trade partner for France, a point Hollande raised at the business forum.
"France is the sixth largest foreign investor in Egypt," he added, addressing French and Egyptian business leaders and officials.
Sisi, in his speech, said Cairo was "working seriously to create an attractive environment for foreign investors", adding that trade between the two countries was 2.58 billion euros (USD 2.9 billion) last year.
The two leaders on Sunday oversaw the signing of 18 economic memorandums of understanding, and 1.2 billion euros in financing for an extension of Cairo's metro system.
Officials travelling with Hollande said new agreements which could include defence contracts were expected on Monday.
Egypt has proved to be a lucrative market for French military hardware.
It was the first foreign country to buy French-made Rafale warplanes, and also bought two Mistral helicopter carriers.
Hollande revisited the topic of human rights on Monday, saying "France has principles and values".
"But we also want to ensure security and development," he said, referring to jihadist attacks in Egypt and the region.
Yesterday, Hollande said he had raised the case of Italian student Giulio Regeni, whose body was found covered in torture marks in February in Cairo, more than a week after his disappearance.
Since the overthrow of Islamist president Mohamed Morsi in 2013 by the military then led by Sisi, police have waged a bloody crackdown on Islamists that has killed more than 1,000 protesters.
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