Axar suffered the injury while playing football and the BCCI said in a statement that he has been advised rest.
"The All-India Senior Selection Committee named Ravindra Jadeja as the replacement for Axar Patel in the team for the first three ODIs in the five-match series against Australia starting tomorrow i.E. September 17, 2017 in MA Chidambaram Stadium, Chepauk in Chennai," the BCCI said.
"Axar sprained his left ankle during a practice session and has been advised rest. The BCCI medical team is monitoring his recovery," it added.
Jadeja did not figure in the original 16-member Indian squad for the first three ODIs, which was announced on September 10.
The Indian team is without opener Shikhar Dhawan, who has been released from the original 16-man squad to attend to his ailing wife.
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