The 38-year-old rapper unveiled the game, called "Only One", during the launch of his Yeezy Season 3 fashion line and his latest album, The Life of Pablo, in New York.
The game will be based on West's song of the same name which explores a conversation between his deceased mother and his daughter North, reported Daily Mirror.
Donda died in 2007 following complications from plastic surgery.
The game, which was announced at the beginning of last year, will explore his mother's journey to heaven.