The Kurdish People's Protection Units (YPG) and its Arab allies ousted Islamist and other rebel fighters from the Minnigh air base and the adjacent town, north of Syria's second city Aleppo, the Syrian Observatory for Human Rights said.
The advance comes after days of fierce clashes that saw YPG forces advance east from the Kurdish stronghold of Afrin and take over a series of villages before reaching Minnigh.
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"Minnigh airport lies between two key roads that lead from Aleppo city to Azaz" to the north, giving Kurdish fighters a strategic launching pad for offensives against jihadists further east, Abdel Rahman added.
Government forces lost control of the Minnigh airport in August 2013, two years after the uprising in Syria first erupted.
Rebel groups are facing a dual advance by both Kurdish forces coming from the west and regime troops - backed by a barrage of Russian air strikes - pressing an offensive north from Aleppo city.
More than 500 people have been killed since the government began its assault on February 1, the observatory said yesterday.
YPG forces regularly clash with Islamist and jihadist fighters in northern Syria, but its most active front is further east against the Islamic State extremist group.
Arab rebel groups have accused Kurdish fighters of ethnically cleansing towns to carve out autonomous Kurdish territories, a claim the YPG has fiercely denied.
More than 260,000 people have been killed and half of the population has been displaced.
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