Klein, a renowned Beverly Hills dermatologist, died on Thursday night, reported TMZ.
The physician, who was suffering from multiple sclerosis, was admitted to a hospital in Palm Springs four days ago, according to law enforcement sources.
He was suffering severe abdominal pains, and remained in the hospital until he died Thursday evening. He was pronounced dead, of natural causes, at 7:50 pm.
Klein was wheelchair bound when he arrived at the hospital.
He was one of Jackson's closest friends, often spending holidays with him and his children.
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