Smriti sustained an injury while playing in the Big Bash League in Australia and Mona will replace her in the 14-member Indian squad to be led by Mithali Raj.
"BCCI medical team confirms that Smriti Mandhana is ruled out of the ICC Women's World Cup Qualifiers to be played in Colombo from February 7, 2017. She sustained an injury during the Big Bash League in Australia," the BCCI said in a release.
India have been placed in Group A alongside Sri Lanka, Ireland, Zimbabwe and Thailand in the February 3-21 event. Group B comprises South Africa, Pakistan, Bangladesh, Scotland and PNG.
India will play a warm-up match against South Africa before their opening Qualifier against Sri Lanka on February 7.
Each side will play four matches in the first round, following which the top three sides from each group will progress to the Super Six stage, while also carrying forward points they earn against sides which have progressed to the Super Six stage from their group.
The World Cup will be staged in the UK from June 26 to July 23.
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