Nesarikar is the fourth senior official the department has lost after the Kalbadevi blaze.
His condition started deteriorating since last evening and he succumbed to injuries, an official from Municipal Corporation of Greater Mumbai (MCGM) said.
He was undergoing treatment at the National Burns Centre in Airoli in Navi Mumbai.
Nesarikar passed away due to multi-organ failure after sustaining 50 per cent third degree burns with acute inhalation lung injury, a hospital official said.
The Kalbadevi fire had also claimed the lives of assistant divisional fire officer S W Rane and station officer MN Desai on May 9.
