Almost five hours later, the great Spaniard was nursing a weighty dose of hurt pride as yet another Wimbledon campaign slipped away from him.
His dramatic 6-3, 6-4, 3-6, 4-6, 15-13 fourth round defeat against Luxembourg's 16th seed Muller was his fifth exit before the quarter-finals in his last five visits to the All England Club.
It was a heartbreaking blow for Nadal who arrived at the tournament fresh from a record-setting 10th French Open title with genuine belief that he could capture a third Wimbledon title and a 16th career major.
"I never said I am not going to come back. I want to come back because I want to play more times in the Centre Court," said Nadal.
Nadal feels he owes his fans a successful last hurrah at a tournament where he has also been runner-up on three occasions.
"Great feeling. Great atmosphere. I put everything on the court. I played with all my passion. The crowd normally appreciate that," said the 2008 and 2010 champion.
World number two Nadal converted just two of 16 break points, while Muller fired 30 aces and 95 winners.
Muller's reward is a first Wimbledon quarter-final appearance against former US Open champion Marin Cilic.
In a pulsating final set, which stretched to 95 minutes, Nadal saved two match points in 10th game and two more in the 20th.
In between, Muller had to fight off a break point in the 13th game and four more in the 19th.
Nadal was always chasing the score and he finally cracked in the 28th game of the decider when he went long with a return.
"It's true that I played some good matches, but the same time is true that I didn't want to lose that match.
"So it is tough to analyse that in a positive way right now. I played better than other years, true. At the same time I was ready for important things, so I lost an opportunity."
For late-bloomer Muller, Monday's sensational win ended a 22-match losing streak against top-five players.
It also came four years after his ranking nosedived to 366 in the world as he battled a potentially career-ending elbow injury.
"The last injury I had was probably the best thing that ever happened to me. Because I had problems with my elbow, I wasn't able to touch a racquet.
"I was able to work out physically, I got myself into the best shape I ever was. Since 2014 when I came back, I'm able to play full seasons without any breaks during the season.
"I have a lot of confidence in my body now, which I didn't do before.
Disclaimer: No Business Standard Journalist was involved in creation of this content
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