McAdams, 36, is set for the lead female in the movie, reported Ace Showbiz.
Although there is no confirmation yet, there are some speculation about the role McAdams will portray in the film.
The movie is currently in pre-production, and director Scott Derrickson is prepping the movie to start shooting in London soon.
Tilda Swinton is attached as the Ancient One, and Chiwetel Ejiofor is set to play the villainous Baron Mordo in the movie.
"Doctor Strange" will follow the story of neurosurgeon, Strange, who after a horrific car accident, discovers the hidden world of magic and alternate dimensions.
McAdams is currently starring on "True Detective" season 2 as Detective Ani Bezzerides. She also stars in boxing movie "Southpaw" alongside Jake Gyllenhaal which will be released later this month.
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