McGowan has been vocal in her criticism of Weinstein since the New York Times expose on the studio honcho.
She was named among the eight women in the article who allegedly reached a private settlement with Weinstein following an undisclosed incident in a hotel room during the Sundance Film Festival in 1997.
In her tweets, McGowan alleged that Amazon Studios optioned a TV series from her and then killed it after she voiced concern to executives about Weinstein who was behind two of the programmes on the streaming platform, reported Variety.
"I told the head of your studio that HW raped me. Over & over I said it. He said it hadn't been proven. I said I was the proof," McGowan wrote.
"I had already sold a script I wrote to your studio, it was in development. When I heard a Weinstein bailout was in the works... I forcefully begged studio head to do the right thing. I was ignored. Deal was done. Amazon won a dirty Oscar," she alleged.
McGowan said she finally decided to get her script back but she she was informed by the studio that her show had been killed.
Weinstein's representative Sallie Hoffmeister said that Weinstein denies the allegation, saying that "any allegations of non-consensual sex are unequivocally denied by Mr Weinstein.
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