The caution was partly because of the upcoming expiry of derivative contracts slated for Thursday. National output numbers are also due the same day.
Counters such as consumer durables, pharma and oil & gas and PSU stocks took the blows as investors pulled money off the table.
After opening a shade higher, the 30-share Sensex slipped into the red, but regained its composure and settled lower by 105.85 points, or 0.31 per cent, at 33,618.59.
The 50-share NSE Nifty too dropped 29.30 points, or 0.28 per cent, at 10,370.25. During the day, it traded between 10,355.20 and 10,409.55.
"Investors were a little conservative ahead of the Q2 GDP data and F&O (futures and options) expiry slated as on Thursday. PSU banks underperformed due to profit booking after the recapitalisation-led rally," said Vinod Nair, Head of Research, Geojit Financial Services Ltd.
Global shares offered no clear picture. A subdued trend in other Asian bourses amid uncertainty over the US tax bill made investors think twice. Concerns about sustained capital outflows by foreign funds lingered.
NTPC fell the sharpest, plunging 1.88 per cent, followed by Bharti Airtel. Others that brought down the key index were Infosys, Tata Motors, Sun Pharma and ONGC.
Stock of Reliance Communications plunged 3.37 per cent on nervous selling by investors amid reports that China Development Bank has filed insolvency case against the telecom firm, which the company has denied.
But Maruti Suzuki, HDFC, Coal India and Asian Paints stayed in the green and absorbed the overall fall to an extent.
Elsewhere, it was a broadly lacklustre trade in Asian markets. European shares went up in early trade.
The broader markets reflected a better trend. The small- cap index firmed up 0.27 per cent while the mid-cap one finished higher by 0.10 per cent.
Foreign portfolio investors (FPIs) sold shares worth a net Rs 424.77 crore yesterday, as per provisional data. Domestic institutional investors (DIIs) bought equities worth a net Rs 69.40 crore.
Disclaimer: No Business Standard Journalist was involved in creation of this content
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