Asian markets too turned negative as the fallout from Trump's steel and aluminium tariffs continued to spook investors and dampen market sentiment here, brokers said.
The 30-share barometer shed 251.56 points, or 0.73 per cent, to 33,795.38. The gauge had lost 398.81 in the previous three sessions.
The NSE Nifty was trading down by 90.40 points, or 0.86 per cent, at 10,367.95.
The laggards were Yes Bank, Tata Steel, Tata Motors, Coal India, Bharti Airtel, ONGC, HUL, Bajaj Auto, Dr Reddy's HDFC, Asian Paint, Power Grid, M&M and SBI, falling up to 2.28 per cent.
Meanwhile, on a net basis, domestic institutional investors (DIIs) sold shares worth Rs 3.29 crore while foreign portfolio investors (FPIs) bought shares worth Rs 241.85 crore on Thursday, provisional data released by the stock exchanges showed.
In the Asian region, Hong Kong's Hang Seng fell 1.38 per cent, Japan's Nikkei shed 0.65 per cent, while Shanghai Composite Index down 0.35 per cent in their early deals.
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