Domestic shares, however, logged their first weekly gain in three on earnings results, which were in line with market expectations so far, as Sensex rose 261.07 points or 1.03 per cent and Nifty climbed 81.45 points or 1.05 per cent.
The week ended on a negative note as two macroeconomic data raised the prospects that RBI would keep interest rates on hold, sending banking stocks, SBI, ICICI Bank, Axis Bank and HDFC Bank sharply lower.
Meanwhile, acting upon recommendations of the Special Investigation Team on black money, Sebi plans to tighten due diligence requirements for issuance and transfer of P-Notes and put the onus on investors to ensure compliance with anti-money laundering law.
Selling was also seen in Asian and European markets as oil snapped a three-day rally as concerns lingered over global growth prospects.
The BSE Sensex stayed in the negative zone through out the day and touched a low of 25,400.27 before winding up 300.65 points or 1.17 per cent down at 25,489.57, its weakest closing since May 6.
Out of the 30-share Sensex, 27 scrips ended lower.
Major laggards included BHEL, HDFC, Tata Steel, L&T, GAIL, Bharti Airtel, Lupin, Hero MotoCorp, TCS, M&M, RIL, ONGC, Bajaj Auto and Sun Pharma.
Among the BSE sectoral indices, realty fell the most by 2.07 per cent followed by metal 2.04 per cent, capital goods 1.57 per cent, consumer durables 1.43 per cent, banking 1.25 per cent, auto 0.96 per cent and oil&gas 0.86 per cent.
Overseas, key indices in China, Hong Kong, Japan and Singapore slipped between 0.31 per cent and 1.41 per cent.
European markets were also lower with key indexes in France and the UK down by up to 0.63 per cent.
