Retail participation, however, was positive with the BSE mid-cap rising 0.17 per cent and small cap index falling by a marginal 0.03 per cent.
Dealers said caution in bluechips was also seen ahead of macroeconomic data IIP numbers for March and consumer price index (CPI) for April slated to be released tomorrow.
The Sensex after opening down at 25,548.97 slided to a low of 25,409.24. However, value-buying in several bluechips helped trim losses and the index finally settled 175.51 points or 0.68 per cent lower at 25,597.02. The gauge had gained 544 points in the past two sessions.
Besides, a mixed trend in regional markets and Europe, which fell towards a one-month low on drop in crude oil prices, also hit trading sentiment here.
India will begin imposing capital gains tax on investments routed through Mauritius from April next year under a revised tax treaty to curb tax evasion and round-tripping of funds -- a move that may have a significant bearing on capital flows from the island nation.
Among other Asian markets, Japan's Nikkei ended 0.08 per cent higher while China's Shanghai Composite ended 0.16 per cent higher. Hong Kong's Hang Seng closed 0.93 per cent down.
Back home, out of the 30-share Sensex, 23 scrips fell.
Major losers were Bharti Airtel (2.55 pc), SBI (2.30 pc), Tata Motors (2.26 pc), Dr Reddy's (2.02 pc), BHEL (1.87 pc), ITC (1.64 pc), Lupin (1.33 pc), HDFC (1.22 pc), ONGC (1.18 pc), Bajaj Auto (1.10 pc) and Infosys (0.95 pc).
Among BSE sectoral and industry indices, telecom fell by 2.34 per cent, realty 0.88 per cent, power 0.75 per cent, IT 0.72 per cent and teck 0.65 per cent.
The market breadth remained negative as 1,462 stocks ended lower, 1,097 closed higher while 160 ruled steady.
The total turnover rose to Rs 2,574.47 crore from Rs 2,349.59 crore yesterday.
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