US President Donald Trump is due to decide tomorrow whether to permanently lift the sanctions, which his predecessor Barack Obama eased in January.
Obama made their removal dependent on Khartoum's progress in five areas of concern during a six-month review period ending tomorrow.
Sudanese officials say Khartoum has fulfilled the Obama administration's conditions.
"We don't expect any other decision except lifting of the sanctions," Ghandour told state radio late yesterday.
"Anything else will be illogical and unacceptable."
"If the sanctions continue, it will push the armed groups to harden their positions," Ghandour said.
"If the sanctions are lifted they will return to negotiations -- if not, they will prepare for war."
Obama's conditions included improved access for aid groups, counterterrorism cooperation with the US, an end to hostilities against armed groups in Sudan and halting support for insurgents in neighbouring South Sudan.
Washington imposed a complex set of economic sanctions on Sudan in 1997 for its alleged backing of Islamist militant groups.
The US further justified the embargo with accusations that Khartoum was using scorched-earth tactics against ethnic minority rebels in war-torn Darfur -- a region of the size of France.
At least 3,00,000 people have been killed and 2.5 million displaced since fighting erupted in the western region in 2003, the United Nations says.
The conflict broke out when ethnic African rebels took up arms against Khartoum's Arab-dominated government, accusing it of marginalising Darfur.
Thousands more have been killed in similar conflicts in the southern states of Blue Nile and South Kordofan since 2011.
United Nations aid agencies operating in Sudan have backed a full lifting of sanctions, saying they hope for a "positive" decision from Washington tomorrow.
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