Hospitals in rebel-controlled Syrian territory face life-threatening power outages due to air strikes or shortages of the precious fuel used for their generators.
The Union of Medical Care and Relief Organisations (UOSSM) hopes their new solar project can circumvent both challenges.
The UOSSM has installed 480 solar panels at a large hospital in opposition-controlled territory in northern Syria since December, it said, and the project officially went online today.
The medical charity declined to specify the hospital's location out of fear it would be targeted by bombardment.
"Patients in this hospital should never be hurt again because of a power cut," said Makdissi.
The World Health Organization has called Syria the world's most dangerous place for health workers, and hundreds of medical facilities have been destroyed in the six-year war.
Some of the most infamous attacks on medical infrastructure took place as government forces tried to retake second city Aleppo from rebels last year.
One attack there in August left four newborn babies dead after the force of the blast cut off the oxygen supply to their incubators.
According to UOSSM, the panels will help their facility save more than 7,000 litres (1,850 gallons) of expensive diesel each month -- amounting to an average of 20-30 percent of its energy costs.
They will help power care for between 700 and 800 patients.
And in case the power cuts completely, wards like the neo-natal facility, intensive care units, and emergency rooms can still run independently, said Shadi Alshhadeh, head of UOSSM's Switzerland branch.
The hospital's medical staff first thought of installing solar panels in 2014.
"But in reality, this isn't just about energy or the environment. This will allow all critical departments to keep working if there's bombing near the hospitals or if the power cuts," he said.
UOSSM will now seek about $1.5 million to fund solar panels at five more hospitals in rebel-held areas of northern Syria.
The conflict in Syria erupted in March 2011 with widespread anti-government protests, but it has since evolved into a multi-front civil war.
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