The television festival is being held from October 11 through October 19 in New York City, and will celebrate current and past television programmes, according to Entertainment Weekly.
Simon will be joined by The Wire stars Wendell Pierce, Sonja Sohn, Seth Gilliam and Jim True-Frost at the Paley Centre for Media on October 16.
Lawrence Gilliard Jr, Michael K Williams, Jamie Hector, John Doman and executive producer Nina Kostroff Noble are to be in attendance as well.
Dominic West - who famously played the renegade cop Jimmy McNulty - is expected to send in a video message.
