The drone targeted compound in Shawal region of North Waziristan, one of seven tribal district, where Pakistan military is engaged in an operation against al-Qaeda-linked militants.
A security official said that militants linked to Hafiz Gul Bahadur Taliban group were targeted, killing eight of them. The exact identity of those killed was not known yet.
Shawal is a mountainous region on Pak-Afghan border where al-Qaeda militants are still hiding despite a relentless military campaign by Pakistan army, which killed more than 1,500 militants since start of an operation in June last year.
North Waziristan has long been used as shelter by the Taliban and al-Qaeda-linked militants and has frequently been targeted by US drones.
For almost a decade, American drone strikes in Pakistan's tribal belt have been deeply unpopular with the public.
Pakistani officials have publicly condemned the drone strikes, saying they violate sovereignty.
