But Google parent Alphabet rose 4.1 per cent to surpass Apple as the world's most valuable company after reporting a five per cent rise in fourth-quarter earnings to USD 4.92 billion.
About 45 minutes into trade, the Dow Jones Industrial Average was at 16,196.54, down 252.64 points (1.54 per cent).
The broad-based S&P 500 fell 26.97 (1.39 per cent) to 1,912.41, while the tech-rich Nasdaq Composite Index shed 52.83 (1.14 per cent) at 4,567.53.
Dow member ExxonMobil fell 2.8 per cent after reporting a 58 per cent drop in fourth-quarter earnings to USD 2.8 billion.
Mid-sized oil producer Anadarko Petroleum rose about 0.5 per cent after reporting a USD 1.3 billion loss for the fourth quarter.
The sell-off in US equities followed even deeper declines in European stock markets. Analysts said another drop in oil prices today was responsible for the poor sentiment.
Dow member Pfizer declined 0.5 per cent as it reported a 50 per cent drop in fourth-quarter earnings to USD 613 million due to higher expenses and the strong dollar.
Royal Caribbean Cruises sank 13.0 per cent after it projected 2016 earnings of USD 5.90-USD 6.10 per share, below the USD 6.27 expected by analysts. Rival firm Carnival fell 6.6 per cent.
Yahoo fell 2.4 per cent on a report that the technology company plans to cut 15 per cent of its workforce, or 1,600 jobs.
After better-than-expected earnings, Dow Chemical rose 1.7 per cent, UPS gained 1.3 per cent and Michael Kors vaulted 16.3 per cent.
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