The mudslide happened late Wednesday in the town of Tamahu, in the northern Alta Verapaz region, a spokesman for the CONRED agency told reporters.
It had been triggered by heavy rains and a swollen river.
Police, soldiers, firemen and volunteers were searching for the eight missing people, who are feared to be buried under tons of mud, the spokesman said.
Two hundred people and 25 homes were affected by the mudslide, and authorities opened a shelter to house them.
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