Outlining other results, US Secretary of State John Kerry said participants set a June 1 deadline for the resumption of humanitarian aid to areas cut off from the outside world.
If land routes remain blocked, food aid will be air dropped and international pressure will be increased on those blocking such relief, he said.
Such pressure will also be applied to stop indiscriminate use of force by the Syrian military, Kerry added, without specifying what pressure the powers could apply.
Kerry said as much to reporters, declaring that to end the conflict "a variety of competing interests are going to have to be reconciled."
"Those involved in this conflict with competing agendas are going to have to prioritize peace," he said.
One key division continues to be the fate of Syrian President Bashar Assad. Going into the talks, German Foreign Minister Frank-Walter Steinmeier repeated the position held by the West and the Saudi-backed opposition that a peace agreement should outline steps leading to the end of his rule.
Kerry did not directly mention Washington's public position that any comprehensive peace agreement must set a timetable for Assad's removal, saying only that "without a negotiated solution, Assad and his supporters will never end the war."
And he questioned suggestions that Assad was immune from international pressure to agree to a settlement. Any such conclusion by the Syrian leader is "without any foundation whatsoever, and it's very dangerous."
"But he has yet to live up to the first one, which is to participate fully in the Geneva talks on a political transition," he said.
The diplomats also called on all parties to dissociate themselves from the Islamic State and the al-Qaida affiliate, known as the Nusra Front, Kerry said.
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