The Sensex has opened lower by 145 points at 19,204 mark and the Nifty slipped by 45 points at 5,710 levels.
Bharti Airtel has dropped by nearly 2% post the announcement of Q1 numbers. The company has reported a 9.6% drop in net income at Rs 689 crore during April-June quarter.
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On the global front, the S&P 500 and Nasdaq ended higher on Tuesday, lifted by gains in the technology sector, while potash shares were the day's big losers.
The tech sector index rose 0.7%, leading the S&P 500's advance. Facebook's stock jumped 6.2% to close at $37.63, within striking distance of its $38 IPO price.
The stock - the most actively traded on Nasdaq - rose as much as 7% to a session high of $37.96. Facebook's stock has gained 42% since the company reported blowout quarterly results last Wednesday.
Japan's Nikkei share average fell on Wednesday morning, as most investors adopted a wait-and-see stance ahead of another batch of key domestic earnings and the outcome of a Federal Reserve policy meeting for clarity on US economic stimulus.
The benchmark Nikkei declined 1% to 13,736.76 in midmorning trade, erasing much of its 1.5% advance on Tuesday, but was still on course for a first monthly gain in three months. The broader Topix fell 0.8% to 1,141.69.
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