Here's what happens to infants born to mothers breathing polluted air

Air pollution not only poses several health risks but is also found to have adverse effects on infants born to mothers exposed to polluted air.

Mothers-to-be who are exposed to particulate air pollution during pregnancy are likely to deliver infants who show reduced cardiac response to stress, according to a study published in the journal Environmental Health Perspectives.

Variability in how the heart rate responds to stressful experiences is essential for maintaining optimal functioning of the cardiovascular, respiratory, and digestive systems and also is central to emotional well-being and resilience to stress over one's lifetime.

Decreased heart rate variability, as observed in this study, is a known risk factor for mental and physical health problems in later life. Air pollution's negative effect on heart rate variability has previously been found to lead to medical and psychological conditions such as heart disease, asthma, allergies, and mood or behavioral disorders in studies of older children, adolescents, and adults.

Researchers in this study took into account 237 Boston-based mothers and their infants and used satellite data and air pollution monitors to determine the level of particulate air pollution the mothers were exposed to during pregnancy.

By studying the babies' heart rate and respiration at age six months, researchers found that the higher the level of the mother's exposure to air pollution in pregnancy, the less variability in the infant's heart rate in response to a stress challenge.

"These findings, in combination with increasing worldwide exposure to particulate air pollution, highlight the importance of examining early-life exposure to air pollution in relation to negative medical, developmental, and psychological outcomes," said senior author Rosalind Wright, MD, MPH, Dean for Translational Biomedical Research, and Professor of Pediatrics, Environmental Medicine and Public Health, and Medicine (Pulmonary, Critical Care and Sleep Medicine), at the Icahn School of Medicine at Mount Sinai.

"Identifying exposures that disrupt key processes such as heart rate response will lead to prevention strategies early in life when they can have the greatest impact," said first author, Whitney Cowell, PhD, a postdoctoral fellow in Environmental Medicine and Public Health at the Icahn School of Medicine.