Palestinians protesting against the raid in the territory's main northern city of Nablus hurled stones at soldiers, who responded with rubber bullets, tear gas and live ammunition, the sources said.
The Palestinian Red Crescent said "10 people were wounded by live rounds to the legs or stomach," and "four others were wounded in beatings" by security forces.
Tensions have soared in the West Bank since the settler couple were shot dead in their car in front of their four children on Thursday evening.
Israel has launched a huge manhunt for the gunmen, and deployed troop reinforcements to maintain order following revenge attacks by settlers.
Palestinian police said today's violence began when "dozens of Israeli soldiers in military vehicles" entered an eastern neighbourhood of Nablus, one of the largest cities in the West Bank.
"They arrested eight people and conducted searches, entering properties by force and causing damage," the police said.
An Israeli military spokeswoman said she was unable to comment on the raid.
Apprehensive of rising tensions between settlers and Palestinians after Thursday's shooting, the Israeli army said it had deployed "four battalions in order to prevent an escalation of violence in the area adjacent to the location of the attack".
And in the Palestinian village of Beitillu, assailants torched a car and spray-painted "Revenge Henkin" in Hebrew on a wall, the army said, adding that nobody was hurt.
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