The ceasefire, announced by the US and the UN hours earlier, took effect at 8:00 AM (0500 GMT) today. US Secretary of State John Kerry cautioned there were "no guarantees" that the lull would bring an end to the Gaza war, now in its fourth week.
Israel and Hamas both said they would respect the ceasefire but would respond to attacks.
At least four short humanitarian ceasefires have been announced since the conflict began, but each has been broken within a few hours by renewed fighting.
He said the family members were killed in an airstrike on their home in the southern Gaza town of Khan Younis.
Israel's military said five of its soldiers were killed along the Gaza border last evening when a mortar round was fired at them.
More than 1,450 Palestinians have been killed since hostilities began July 8, according to Palestinian officials.
Israel says 61 of its soldiers and three civilians in Israel have been killed.
Tank shells landed on homes in the city, setting homes and shops ablaze.
Hamas fighters hit an Israeli tank with an anti-tank missile, Gaza police said, and then attacked Israeli troops who came to evacuate the tank crew. Clashes continued into the early morning hours, police said. The Israeli military said it was looking into the matter.
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