The mishap took place in el-Saf city near Menya Governorate. The bus was on its way to Cairo from Menya.
The driver was rashly driving and could not control the the steering near a bend and the bus turned turtle, primary investigations said.
Security forces and ambulances rushed to the spot and transferred injured to hospitals.
Early this month, two major accidents killed at least 28 people.
Following these accidents, President Abdel Fattah el-Sisi assigned a specialist council for community development to devise a new scheme to minimise road accidents.
Amendments includes a penalty of a minimum of one year in prison for driving under the influence of drugs, and if the driver injures one or more persons he may get at least two years in prison.
Egypt has one of the world's highest accident rates owing to careless driving and poor road and vehicle conditions.
