The 33-year-old star has joined an ensemble that includes Natalie Portman, Jessica Chastain, Thandie Newton, Kit Harington, Susan Sarandon, Kathy Bates, Jacob Tremblay, Michael Gambon, Bella Thorne, Chris Zylka and Emily Hampshire.
In the movie, Karan will play Mrs Kureishi, an English teacher who shows interest in one of her students who is being bullied at school, reported Deadline.
The film's screenplay has been written by Dolan, who is known for his critically acclaimed Quebec biographical drama "I Killed My Mother".
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