Releasing its 408-page annual report on rights abuses around the world today, the watchdog group described 2016 as "the year when the cynical use of 'us vs. Them' narratives of blame, hate and fear took on a global prominence to a level not seen since the 1930s," when Adolf Hitler rose to power in Germany.
Amnesty named Trump, Hungarian Prime Minister Viktor Orban, Turkish President Recep Tayyip Erdogan and Philippines President Rodrigo Duterte among leaders it said are "wielding a toxic agenda that hounds, scapegoats and dehumanizes entire groups of people."
"The limits of what is acceptable have shifted. Politicians are shamelessly and actively legitimizing all sorts of hateful rhetoric and policies based on people's identity: misogyny, racism and homophobia. The first target has been refugees and, if this continues in 2017, others will be in the crosshairs."
The White House did not respond to a request for comment on the report.
Amnesty's annual report, "The State of the World's Human Rights," documented what it called "grave violations of human rights" in 159 countries in 2016.
The report added that "the big question in 2017 will be how far the world lets atrocities go before doing something about them."
Exceptionally, London-based Amnesty chose to launch its report in Paris.
Salil Shetty, the group's secretary-general, said France has used emergency powers introduced in 2015 in the wake of terror attacks in an abusive and "deeply discriminatory" manner, confining more than 600 people, mostly Muslins, under house arrest and banning more than 140 protests.
France's government has repeatedly defended the emergency powers as a necessary safeguard against the severe terror threat it says is facing the country, and parliament has repeatedly voted to extend those powers.
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