As Europe and the United States struggle to contain the coronavirus pandemic, aid groups warn that without measures millions could die in low-income countries and war zones such as Syria and Yemen, where hygiene conditions are already dire.
The outbreak has infected some 580,000 people and killed over 26,000 around the world after emerging in China in December last year.
Across Africa, the official numbers are still relatively low with 83 deaths and over 3,200 confirmed cases on Friday, according to the African Union.
But aid groups are sounding the alarm on the potentially devastating consequences of a severe outbreak in low-income and conflict-ridden countries, where healthcare systems are in tatters and hygiene conditions poor.
"Refugees, families displaced from their homes, and those living in crisis will be hit the hardest by this outbreak," said the International Rescue Committee (IRC) in a statement.
Misty Buswell from the IRC said areas like the last rebel-held province in war-torn Syria, Idlib, which was already enduring a humanitarian crisis before the pandemic started, were particularly at risk.
"A lack of food, clean water and exposure to cold weather have already left hundreds of thousands of people in poor health, making them even more vulnerable," said Buswell, adding the devastation in Idlib could be "unimaginable".
Around the world three billion people lack access to running water and soap, which are the most basic weapons of protection against the virus, UN experts warned.
"Frequently washing hands is the most effective way to protect against the coronavirus, but what will more than half the Yemeni people who don't have access to safe water do?" the International Committee of the Red Cross in Yemen tweeted Sunday.
UN Secretary General Antonio Guterres issued a stark warning last week: "If we let coronavirus spread like wildfire -- especially in the most vulnerable regions of the world -- it would kill millions of people."
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