The Bible was part of a fine books and manuscripts auction at Bonhams. The German-born, Nobel Prize-winning physicist and his wife signed it in 1932 and gave it to a US friend, Harriett Hamilton.
The auction house says Einstein writes in the German inscription the Bible "is a great source of wisdom and consolation and should be read frequently."
The Bible's final price far exceeds its pre-sale estimate of between USD 1,500 and USD 2,500.
The auction house hasn't said who bought the Bible.