The woman was diagnosed in Yueyang City yesterday.
She had contact with poultry before falling ill and is in critical condition, according to the provincial disease control and prevention centre.
People who had close contact with the patient have not shown symptoms of fever or coughing, state-run Xinhua news agency reported.
In addition to Hunan, human H7N9 infections have also been reported in the provinces of Guangdong, Guizhou, Hubei, Henan, Jiangxi and Shandong, as well as in Shanghai, Hong Kong and Macao.
It is most likely to strike in winter and spring.
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