IM Global will finance the film with Wilson and Broccoli producing through their Eon Productions banner, with IM Global co-founder Stuart Ford executive producing along with Greg Shapiro and Mark Burnell, reported Variety.
The movie is a contemporary adaptation of the first of Burnell's "Stephanie Patrick" British series of four novels.
Lively will play the titular heroine, who's on a path to self-destruction after the death of her family in an airplane crash - a flight that she was meant to be on.
"We are thrilled to be bringing Mark Burnell's 'The Rhythm Section' to the big screen with our partners at IM Global," Broccoli and Wilson said.
"It is exciting for us to be working with the immensely talented team of director Reed Morano and actress who have a strong vision for this very compelling story driven by a female protagonist."
Morano received critical acclaim for helming several episodes of the hit Hulu series "The Handmaid's Tale."
The film will begin production this fall and will likely shoot in the US, the UK, Ireland, Spain, and Switzerland.
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